Document Detail

Placental pathology and abnormal fetal heart rate patterns in gestational diabetes.
MedLine Citation:
PMID:  2813198     Owner:  NLM     Status:  MEDLINE    
Infants of diabetic mothers are considered to be at increased risk of fetal distress. We suggest that umbilical vasculitis is strongly associated with abnormal fetal rate patterns, which indicate fetal tissue hypoxia even in the absence of clinical evidence of intrapartum infection. In the present series, 132 term deliveries with Class A diabetes mellitus were compared with 159 uncomplicated term deliveries. Umbilical vasculitis and gestational age greater than 281 days were both highly correlated with abnormal fetal heart rate patterns in diabetic pregnancies (p less than 0.001). These effects were shown to be independent by multiple logistic regression. There was no difference in mean birthweight between infants of diabetic mothers and those of uncomplicated pregnancies, but infants of diabetic mothers had heavier placentas (p less than 0.01). These data further support our hypothesis that umbilical vasculitis may affect umbilical hemodynamics and predispose to development of fetal heart rate patterns.
C M Salafia; L Silberman
Related Documents :
3914818 - Obstetric care in diabetic pregnancy.
9433048 - Statistical analysis of perinatal outcomes in pregnancy complicated with diabetes melli...
15209118 - Fetal and embryonic hemoglobins in erythroblasts from fetal blood and fetal cells enric...
15101608 - The safety and efficacy of insulin analogs in pregnancy.
18191798 - Male reproductive proteins and reproductive outcomes.
19626028 - Medical and ethical considerations in twin pregnancies discordant for serious cardiac d...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric pathology / affiliated with the International Paediatric Pathology Association     Volume:  9     ISSN:  0277-0938     ISO Abbreviation:  Pediatr Pathol     Publication Date:  1989  
Date Detail:
Created Date:  1989-12-21     Completed Date:  1989-12-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8303527     Medline TA:  Pediatr Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  513-20     Citation Subset:  IM    
Department of Laboratory Medicine, Danbury Hospital, CT 06810.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Bacterial Infections / complications
Chorioamnionitis / pathology
Heart Rate, Fetal*
Infant, Newborn
Placenta / pathology*
Pregnancy Complications, Infectious / pathology
Pregnancy in Diabetics / pathology*,  physiopathology
Umbilical Cord / pathology
Vasculitis / pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Renal lesions and clinical findings in thalassemia major and other chronic anemias with hemosiderosi...
Next Document:  Morphological nature of the atrioventricular valves in hearts with double inlet left ventricle.