Document Detail


Placental isoferritin in pregnancies with small-for-gestational age fetuses.
MedLine Citation:
PMID:  8843474     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The secretion of placental isoferritin (PLF) during pregnancy could be responsible for the diminished immunoreaction of maternal lymphocytes against the embryo. In this study, serum levels of PLF in 335 pregnant women were correlated with birth weight, percentile of birth weight, gestational age, and pulsatility index of the uterine artery, as well as with diastolic notching. Women with small-for-gestational age (SGA) infants (birth weight below or equal to the tenth percentile) showed significantly lower PLF levels (11.7 U/ml) compared with women whose newborns were of normal weight (19.4 U/ml) (P < 0.05). In line with this finding, a strong correlation was observed between PLF levels and the percentile of birth weight, pulsatility index of the uterine artery, and the presence of diastolic notching. The strong correlation of low PLF values and SGA newborns suggests that determination of PLF could serve as a marker to identify women at risk of having such babies.
Authors:
A C Rosen; E Hafner; L Auerbach; H R Rosen; K Schuchter; K Huber; C Ausch; C Moroz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Prenatal diagnosis     Volume:  16     ISSN:  0197-3851     ISO Abbreviation:  Prenat. Diagn.     Publication Date:  1996 Jul 
Date Detail:
Created Date:  1996-12-31     Completed Date:  1996-12-31     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8106540     Medline TA:  Prenat Diagn     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  641-6     Citation Subset:  IM    
Affiliation:
Ludwig Boltzmann Institute of Clinical Obstetrics and Gynaecology, SMZ-Ost Medical Center Vienna, Austria.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Arteries / physiology
Birth Weight
Cytokines / blood,  secretion*
Female
Ferritins / blood,  secretion*
Fetal Growth Retardation / diagnosis*
Humans
Multivariate Analysis
Placenta / secretion*
Pregnancy
Pulsatile Flow
ROC Curve
Sensitivity and Specificity
Uterus / blood supply*,  physiology
Chemical
Reg. No./Substance:
0/Cytokines; 9007-73-2/Ferritins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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