| Placental intravascular organisms: a case report. | |
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MedLine Citation:
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PMID: 20877362 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Ascending amniotic fluid bacterial infection is a cause of perinatal morbidity and mortality. A diagnosis of amniotic cavity infection can be inferred by documenting maternal (acute chorioamnionitis) and/or fetal (chorionic plate vasculitis; umbilical vasculitis/funisitis) inflammatory response. A definitive diagnosis of intrauterine/neonatal sepsis as a cause of stillbirth requires positive blood cultures obtained at postmortem examination. However, if postmortem examination is not performed, acute chorioamnionitis with/without fetal inflammatory response cannot be classified as a cause of demise. We present a case of intrauterine demise associated with acute chorioamnionitis, villitis, and intervillositis of the placenta. Although postmortem examination was denied, a conclusive diagnosis of intrauterine sepsis could be rendered by demonstration of gram-positive cocci within fetal vessels of umbilical cord, chorionic plate, and stem villi. This report highlights the importance of identification of placental intravascular organisms as unequivocal evidence of fetal sepsis, especially in cases where cultures cannot be obtained. |
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Authors:
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A Matoso; S Shapiro; M E De Paepe; F Gundogan |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of perinatology : official journal of the California Perinatal Association Volume: 30 ISSN: 1476-5543 ISO Abbreviation: J Perinatol Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-09-29 Completed Date: 2011-01-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8501884 Medline TA: J Perinatol Country: United States |
Other Details:
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Languages: eng Pagination: 688-90 Citation Subset: IM |
Affiliation:
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Department of Pathology, Rhode Island Hospital, Providence, RI, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Amniotic Fluid / microbiology Chorioamnionitis Chorion / microbiology Chorionic Villi / microbiology, pathology Diseases in Twins / microbiology* Female Fetal Death / microbiology* Fetal Diseases / microbiology* Humans Placenta / microbiology Pregnancy Pregnancy Complications, Infectious Pregnancy Trimester, Second Retrospective Studies Sepsis / diagnosis*, microbiology Stillbirth* Umbilical Cord / blood supply, microbiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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