Document Detail

Placental abruption and perinatal death.
MedLine Citation:
PMID:  11489159     Owner:  NLM     Status:  MEDLINE    
Studies of risk factors for abruptio placentae (AP) are partly conflicting and studies of risk factors for perinatal death in these pregnancies are scarce. Using the population-based Swedish Birth Registry from 1987 to 1993, we were able to study these risks in 795,459 singleton pregnancies. Logistic regression analysis was used to estimate odds ratios (OR) for risk of AP and risk of perinatal death in pregnancies with and without AP. Risk factors for AP were: age, primiparity, high parity, not cohabiting with infant's father, low education, smoking, infertility, pregestational diabetes, essential hypertension, pregnancy-induced hypertensive diseases, preterm premature rupture of membranes, preterm birth and small-for-gestational-age (SGA) births. Risk factors for perinatal death in pregnancies with placental abruption were smoking (1--9 and > or =10 cigarettes/day; OR 1.4 and 1.7 respectively), severe pre-eclampsia (OR 2.0) and SGA (OR 1.9), whereas in pregnancies without abruption, risks were also increased in maternal age > or =35 years, primiparity, infertility, essential hypertension and pregestational diabetes. These findings support the theory that, in cases of AP, a general impairment of the placenta and/or a defect placentation may be fatal.
N B Kyrklund-Blomberg; G Gennser; S Cnattingius
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Paediatric and perinatal epidemiology     Volume:  15     ISSN:  0269-5022     ISO Abbreviation:  Paediatr Perinat Epidemiol     Publication Date:  2001 Jul 
Date Detail:
Created Date:  2001-08-07     Completed Date:  2001-09-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8709766     Medline TA:  Paediatr Perinat Epidemiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  290-7     Citation Subset:  IM    
Karolinska Institutet Danderyd Hospital, Division of Obstetrics and Gynaecology, Stockholm, Sweden.
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MeSH Terms
Abruptio Placentae / epidemiology*
Data Collection
Data Interpretation, Statistical
Infant Mortality*
Infant, Newborn
Logistic Models
Odds Ratio
Pregnancy Complications / epidemiology
Risk Factors
Socioeconomic Factors
Sweden / epidemiology

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