| Placental abnormalities and preeclampsia in trisomy 13 pregnancies. | |
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MedLine Citation:
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PMID: 19346185 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Women who are carrying a trisomy 13 fetus are prone to have an abnormal placenta as well as to develop preeclampsia in the second and third trimesters. This article provides a comprehensive review of placental abnormalities, such as small placental volume, reduced placental vascularization, a partial molar appearance of the placenta and placental mesenchymal dysplasia, and preeclampsia associated with trisomy 13 pregnancies. The candidate preeclampsia-causing genes on chromosome 13, such as sFlt1, COL4A2 and periostin, are discussed. |
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Authors:
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Chih-Ping Chen |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Taiwanese journal of obstetrics & gynecology Volume: 48 ISSN: 1875-6263 ISO Abbreviation: - Publication Date: 2009 Mar |
Date Detail:
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Created Date: 2009-04-06 Completed Date: 2009-07-17 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 101213819 Medline TA: Taiwan J Obstet Gynecol Country: China |
Other Details:
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Languages: eng Pagination: 3-8 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, Taiwan. cpc_mmh@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cell Adhesion Molecules
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genetics Chromosomes, Human, Pair 13 / genetics* Collagen Type IV / genetics Female Humans Placenta Diseases* Pre-Eclampsia / genetics* Pregnancy Trisomy* Vascular Endothelial Growth Factor Receptor-1 / genetics |
| Chemical | |
Reg. No./Substance:
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0/Cell Adhesion Molecules; 0/Collagen Type IV; 0/POSTN protein, human; EC 2.7.10.1/FLT1 protein, human; EC 2.7.10.1/Vascular Endothelial Growth Factor Receptor-1 |
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