Document Detail


Placental Ultrastructural Changes and Apoptosis in Pregnancies with Meconium Stained Amniotic Fluid.
MedLine Citation:
PMID:  22627633     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Objective: The cause of meconium stained amniotic fluid in term healthy pregnancies is not clearly understood yet. The aim of this study was to investigate the placental ultrastructural changes and placental apoptosis in pregnancies complicated with meconium stained amniotic fluid. Material and Method: The study group was composed of mothers (n: 13) and their term, appropriate for gestational age newborns with meconium stained amniotic fluid but without meconium aspiration syndrome. The control group consisted of mothers (n: 24) and their term appropriate for gestational age babies. We studied placental ultrastructural changes by transmission electron microscopy and placental apoptosis by transmission electron microscopy and the TUNEL method. Results: The incidence of placental apoptosis by the TUNEL method was significantly higher in the study group compared to the control group. Transmission electron microscopy investigation revealed more remarkable ultrastructural changes in the study group compared to the control group. Conclusion: The increased apoptosis and ultrastructural findings in placentas with meconium stained amniotic fluid may be related to the placental adaptation to the hypoxic fetuses.
Authors:
Ziya Yurdakul; Hüseyin Kemal Türköz; Hülya Bılgen; Seyhun Solakoğlu; Sultan Kavuncuoğlu; Eren Ozek
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Turk patoloji dergisi     Volume:  28     ISSN:  1018-5615     ISO Abbreviation:  -     Publication Date:  2012  
Date Detail:
Created Date:  2012-5-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9440471     Medline TA:  Turk Patoloji Derg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  147-153     Citation Subset:  -    
Affiliation:
Department of Pediatrics, Marmara University, Faculty of Medicine, İSTANBUL, TURKEY.
Vernacular Title:
Mekonyumlu Amnion Sıvısı Olan Gebeliklerde Plasental İnce Yapısal Değişiklikler ve Apoptozis.
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