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The Placental Factor in Spontaneous Term Labor in Uncomplicated Pregnancy.
MedLine Citation:
PMID:  22746184     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract Objectives:To investigate the placental role in uncomplicated pregnancies and spontaneous term labor. Methods: Placentas were retrieved from women with uncomplicated pregnancies and compared between those with spontaneous term labor to those with elective cesarean delivery without labor. Placentas were analyzed for lesions consistent with maternal circulation abnormalities, lesions consistent with fetal thrombo-occlusive disease and inflammatory lesions, maternal or fetal responses. Results: The study included 139 pregnancies, 76 with term spontaneous deliveries (cases) and 63with term elective cesarean deliveries (controls). Maternal age, gravidity, parity and BMI were significantly lower in the study group, but gestational age was higher as compared with the control group. Higherrate of maternal inflammatory lesions was observed in the study group compared to the control group, 21% vs. 1.6%, respectively, p=0.001. No differences were observed in vascular lesions or in fetal inflammatory lesions between the groups. Conclusion:Placental maternal inflammatory changes play a role in spontaneous term labor, different from the involvement of the fetal compartment and placental vascular component in preterm labor.
Authors:
Jacob Bar; Letizia Schreiber; Abraham Golan; Michal Kovo
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-29
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  -     ISSN:  1476-4954     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-7-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Obstetrics & Gynecology, the Edith Wolfson Medical Center, Holon affiliated withSackler Faculty of Medicine, Tel Aviv University, Tel Aviv; Israel.
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