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Placenta and umbilical cord abnormalities seen with stillbirth.
MedLine Citation:
PMID:  20661050     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Placental lesions identified in cases of stillbirth are of clinical interest and are frequently invoked as having a causal role. However, most of the placental changes found in stillbirth are also seen in liveborn pregnancies, and are of uncertain pathogenetic significance. Much of the literature addressing placental lesions found in stillbirth is descriptive, listing cases of interest without adequate controls. Further, lesions are described qualitatively, often with inadequate description of examination and sampling protocols. In this manuscript we describe the placental characteristics that are most frequently listed in stillbirth case series, including entities associated with maternal diseases. First, we describe how macroscopic placental, cord, and membrane findings can provide answers to midwives and physicians at the time of delivery and how the placenta should be handled in the delivery room to optimize the histopathological examination. Second, we provide a brief organization of histological findings of the pathogenesis of conditions associated with fetal death.
Authors:
Halit Pinar; Marshall Carpenter
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical obstetrics and gynecology     Volume:  53     ISSN:  1532-5520     ISO Abbreviation:  Clin Obstet Gynecol     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-07-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0070014     Medline TA:  Clin Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  656-72     Citation Subset:  IM    
Affiliation:
Division of Perinatal and Pediatric Pathology, Brown University, Providence, Rhode Island 02905, USA. hpinar@wihri.org
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