| Placenta percreta: methotrexate treatment and MRI findings. | |
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MedLine Citation:
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PMID: 18176907 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Our patient was a 24-year-old gravida 2 para 0 woman. After delivery, placenta percreta was noticed. There was no postpartum hemorrhage, and the patient desired future pregnancies. Although placenta percreta is rare, its sequelae include potentially lethal hemorrhage and loss of reproduction function. Placenta percreta was confirmed histologically and with ultrasonography and magnetic resonance imaging (MRI). Placenta percreta was treated conservatively with methotrexate. On follow-up, MRI showed a small calcified transmural extension of the placenta throughout the uterus in the right fundal area. Color Doppler ultrasonography showed no blood flow in the corresponding area, and maternal serum human chorionic gonadotropin (hCG) was undetectable. Use of MRI is a new method to detect abnormal placentation, and it could be used on follow-up in selective cases with other follow-up modalities. However, it seems likely that conservative management to preserve future fertility remains a secured and reasonable alternative when a patient has no active bleeding. |
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Authors:
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Nonna Heiskanen; Jaana Kröger; Sakari Kainulainen; Seppo Heinonen |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2008-01-04 |
Journal Detail:
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Title: American journal of perinatology Volume: 25 ISSN: 0735-1631 ISO Abbreviation: Am J Perinatol Publication Date: 2008 Feb |
Date Detail:
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Created Date: 2008-02-14 Completed Date: 2008-05-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8405212 Medline TA: Am J Perinatol Country: United States |
Other Details:
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Languages: eng Pagination: 91-2 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Kuopio University Hospital, Kuopio, Finland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abortifacient Agents
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therapeutic use* Adult Female Humans Magnetic Resonance Imaging* Methotrexate / therapeutic use* Myometrium / pathology Placenta Accreta / diagnosis*, drug therapy* Pregnancy Ultrasonography |
| Chemical | |
Reg. No./Substance:
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0/Abortifacient Agents; 59-05-2/Methotrexate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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