Document Detail

Placement and refined mapping of established and new markers on human chromosome 11q using a small panel of somatic cell hybrids.
MedLine Citation:
PMID:  7767655     Owner:  NLM     Status:  MEDLINE    
Constructing detailed chromosome maps relies on the ability to place new markers rapidly and accurately. Here we map two new anonymous DNA markers precisely on chromosome 11q and refine the location of established markers using a panel of just six fragmentation hybrids, with reference to four translocation chromosomes. As several of the hybrids retain multiple segments of chromosome 11, it is possible to quickly assign new markers to subintervals using this modest set of hybrid DNAs.
K L Evans; V van Heyningen; D J Porteous
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of human genetics : EJHG     Volume:  3     ISSN:  1018-4813     ISO Abbreviation:  Eur. J. Hum. Genet.     Publication Date:  1995  
Date Detail:
Created Date:  1995-07-06     Completed Date:  1995-07-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9302235     Medline TA:  Eur J Hum Genet     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  42-8     Citation Subset:  IM    
MRC Human Genetics Unit, Western General Hospital, Edinburgh, UK.
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MeSH Terms
Base Sequence
Cell Line
Chromosome Aberrations / genetics
Chromosome Mapping*
Chromosomes, Human, Pair 11 / genetics*
DNA Probes / genetics
DNA, Satellite / genetics
Genetic Markers / genetics*
Hybrid Cells*
Molecular Sequence Data
Polymerase Chain Reaction
Reg. No./Substance:
0/DNA Probes; 0/DNA, Satellite; 0/Genetic Markers

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