Document Detail


Placebo-controlled studies in schizophrenia--ethical and scientific perspectives: an overview of conference proceedings.
MedLine Citation:
PMID:  10093863     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Much controversy has surrounded the issue of whether clinical trials of new antipsychotic medications for the treatment of schizophrenia ought to include a placebo control group. On 18 September 1997, the authors co-chaired a symposium at the University of Toronto devoted to elucidating the issues relevant to this debate. Speakers with expertise in the areas of schizophrenia research, clinical trials methodology, medical ethics and informed consent presented their perspectives. This paper aims to summarize the major scientific and ethical issues raised during the symposium.
Authors:
R B Zipursky; P Darby
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Publication Detail:
Type:  Congresses; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Schizophrenia research     Volume:  35     ISSN:  0920-9964     ISO Abbreviation:  Schizophr. Res.     Publication Date:  1999 Feb 
Date Detail:
Created Date:  1999-06-22     Completed Date:  1999-06-22     Revised Date:  2010-09-02    
Medline Journal Info:
Nlm Unique ID:  8804207     Medline TA:  Schizophr Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  189-200     Citation Subset:  E; IM    
Affiliation:
Department of Psychiatry, University of Toronto School of Medicine, Ontario, Canada. rz@sig.clarke-inst.on.ca
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MeSH Terms
Descriptor/Qualifier:
Antipsychotic Agents / therapeutic use*
Clinical Trials as Topic*
Ethics, Medical*
Evidence-Based Medicine
Humans
Informed Consent
Patient Compliance
Recurrence
Research
Schizophrenia / drug therapy*
Chemical
Reg. No./Substance:
0/Antipsychotic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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