Document Detail


Place-specific derived cochlear microphonics from human ears.
MedLine Citation:
PMID:  1439498     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The high-pass noise masking technique was used to obtain derived frequency-specific cochlear microphonics (CM) from subtracted waveforms to rarefaction and condensation stimuli recorded with a tympanic membrane electrode. Two characteristics suggest that the response is place-specific CM: the derived response retains the same frequency as the stimulating toneburst and the response follows the stimulus polarity. For click stimulation, derived neural responses make the place-specific CM difficult to observe except in the 2-1 kHz derived band. In contrast, place-specific CM evoked by 0.5 and 1 kHz tonebursts can usually be detected in at least three derived bands. The amplitude of the response is largest in the derived band with center-frequency (CF) just above that of the toneburst. This discovery of a place-specific CM offers the possibility of assessing (outer) hair cell function in the apical part of the human cochlea.
Authors:
C W Ponton; M Don; J J Eggermont
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Scandinavian audiology     Volume:  21     ISSN:  0105-0397     ISO Abbreviation:  Scand Audiol     Publication Date:  1992  
Date Detail:
Created Date:  1992-12-16     Completed Date:  1992-12-16     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0342230     Medline TA:  Scand Audiol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  131-41     Citation Subset:  IM    
Affiliation:
Electrophysiology Laboratory, House Ear Institute, Los Angeles, California.
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MeSH Terms
Descriptor/Qualifier:
Acoustic Stimulation
Adolescent
Adult
Audiometry, Evoked Response
Cochlea / physiology*
Cochlear Microphonic Potentials*
Evoked Potentials, Auditory, Brain Stem / physiology
Female
Hair Cells, Auditory / physiology
Hearing / physiology
Hearing Disorders / diagnosis*
Humans
Male
Noise
Tympanic Membrane / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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