| Pituitary gland: MR imaging of physiologic hypertrophy in adolescence. | |
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MedLine Citation:
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PMID: 2305049 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The size and shape of pituitary glands in 169 children, adolescents, and young adults were analyzed with T1-weighted sagittal magnetic resonance (MR) images. In patients younger than 12 years old, no pituitary gland was found to be more than 6 mm in height. In adolescents, definite evidence for physiologic (pubertal) pituitary hypertrophy was seen in both sexes, although it was much more prominent in girls. The pituitary glands of four of 32 teenage girls measured 8-10 mm, but no teenage boy had a gland taller than 7 mm. Young adults aged 21-30 years had significantly (P less than .05) smaller glands than teenagers of the same sex. Significant (P = .0001) variations in the shape of the pituitary glands according to patient age and sex were also noted. Convex upper margins were seen in 56% of teenage girls, while this shape was noted in only 18% of the remaining patients of either sex. In eight of 32 teenage girls (25%) the pituitary glands were nearly spherical on sagittal images; this shape was not recorded in any other group. The normal maturation sequence of the pituitary gland apparently involves a period of physiologic hypertrophy in teenagers. This is manifest in girls by a significant change in both pituitary size and shape, while the glands of boys undergo a transformation in size only. |
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Authors:
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A D Elster; M Y Chen; D W Williams; L L Key |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Radiology Volume: 174 ISSN: 0033-8419 ISO Abbreviation: Radiology Publication Date: 1990 Mar |
Date Detail:
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Created Date: 1990-03-27 Completed Date: 1990-03-27 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 681-5 Citation Subset: AIM; IM |
Affiliation:
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Department of Radiology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC 27103. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Child Female Humans Hypertrophy Magnetic Resonance Imaging Male Pituitary Gland / anatomy & histology*, physiology Puberty / physiology* Reference Values |
| Comments/Corrections | |
Comment In:
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Radiology. 1991 Jan;178(1):284-5
[PMID:
1984320
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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