Document Detail

Pituitary carcinoma with liver metastases and Cushing syndrome. Report of a case.
MedLine Citation:
PMID:  1111493     Owner:  NLM     Status:  MEDLINE    
A 38-year-old woman complained of headache, visual impairment, and diabetes insipidus for 18 months prior to rapid onset of Cushing syndrome and amenorrhea. An autopsy disclosed a pituitary carchinoma invading the right cavernous sinus and two liver metastases. The tumor cells were chromophobic and agranular, with scarce polymorphism and rare mitoses. A review of the literature showed that the association of Cushing syndrome to pituitary carcinomas increases in direct proportion to the occurence of metastases. Such association was noted in almost half of the reported cases of pituitary carcinomas with extracranial dissemination.
L de S Queiroz; N O Facure; J J Facure; N P Modesto; J Lopes de Faria
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of pathology     Volume:  99     ISSN:  0363-0153     ISO Abbreviation:  Arch Pathol     Publication Date:  1975 Jan 
Date Detail:
Created Date:  1975-04-16     Completed Date:  1975-04-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7605251     Medline TA:  Arch Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  32-5     Citation Subset:  AIM; IM    
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MeSH Terms
Cavernous Sinus / pathology
Cushing Syndrome / complications*
Liver Neoplasms / complications,  pathology*
Neoplasm Metastasis
Pituitary Neoplasms / complications,  pathology*
Vascular Diseases / pathology

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