| Pituitary autoimmunity: 30 years later. | |
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MedLine Citation:
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PMID: 18774118 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pituitary autoimmunity encompasses a spectrum of conditions ranging from histologically proven forms of lymphocytic hypophysitis to the presence of pituitary antibodies in apparently healthy subjects. Hypophysitis is a rare but increasingly recognized disorder that typically presents as a mass in the sella turcica. It mimics clinically and radiologically other non-functioning sellar masses, such as the more common pituitary adenoma. Hypophysitis shows a striking temporal association with pregnancy, and it has been recently described during immunotherapies that block CTLA-4. Several candidate pituitary autoantigens have been described in the last decade, although none has proven useful as a diagnostic tool. This review summarizes the advances made in the field since the publication of the first review on pituitary autoimmunity, and the challenges that await clarification. |
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Authors:
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Patrizio Caturegli; Isabella Lupi; Melissa Landek-Salgado; Hiroaki Kimura; Noel R Rose |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Review Date: 2008-05-08 |
Journal Detail:
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Title: Autoimmunity reviews Volume: 7 ISSN: 1568-9972 ISO Abbreviation: Autoimmun Rev Publication Date: 2008 Sep |
Date Detail:
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Created Date: 2008-09-08 Completed Date: 2008-12-05 Revised Date: 2013-03-14 |
Medline Journal Info:
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Nlm Unique ID: 101128967 Medline TA: Autoimmun Rev Country: Netherlands |
Other Details:
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Languages: eng Pagination: 631-7 Citation Subset: IM |
Affiliation:
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Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States. pcat@jhmi.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Autoimmune Diseases / immunology*, metabolism Humans Pituitary Diseases / immunology* Pituitary Gland / immunology* Pituitary Hormones / immunology |
| Grant Support | |
ID/Acronym/Agency:
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DK55670/DK/NIDDK NIH HHS; R21 DK080351/DK/NIDDK NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Pituitary Hormones |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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