Document Detail


Pituitary autoimmunity: 30 years later.
MedLine Citation:
PMID:  18774118     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Pituitary autoimmunity encompasses a spectrum of conditions ranging from histologically proven forms of lymphocytic hypophysitis to the presence of pituitary antibodies in apparently healthy subjects. Hypophysitis is a rare but increasingly recognized disorder that typically presents as a mass in the sella turcica. It mimics clinically and radiologically other non-functioning sellar masses, such as the more common pituitary adenoma. Hypophysitis shows a striking temporal association with pregnancy, and it has been recently described during immunotherapies that block CTLA-4. Several candidate pituitary autoantigens have been described in the last decade, although none has proven useful as a diagnostic tool. This review summarizes the advances made in the field since the publication of the first review on pituitary autoimmunity, and the challenges that await clarification.
Authors:
Patrizio Caturegli; Isabella Lupi; Melissa Landek-Salgado; Hiroaki Kimura; Noel R Rose
Related Documents :
15852308 - Foregut glands of solenogastres (mollusca): anatomy and revised terminology.
451568 - C26 sterol in a human urine.
12665708 - Fertility in women with congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
289828 - Histological development of the equine fetal adrenal gland.
12557038 - Fetal wound healing: current biology.
11432108 - Effect of duration of estradiol replacement on the outcome of oocyte donation.
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Review     Date:  2008-05-08
Journal Detail:
Title:  Autoimmunity reviews     Volume:  7     ISSN:  1568-9972     ISO Abbreviation:  Autoimmun Rev     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-09-08     Completed Date:  2008-12-05     Revised Date:  2013-03-14    
Medline Journal Info:
Nlm Unique ID:  101128967     Medline TA:  Autoimmun Rev     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  631-7     Citation Subset:  IM    
Affiliation:
Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States. pcat@jhmi.edu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Autoimmune Diseases / immunology*,  metabolism
Humans
Pituitary Diseases / immunology*
Pituitary Gland / immunology*
Pituitary Hormones / immunology
Grant Support
ID/Acronym/Agency:
DK55670/DK/NIDDK NIH HHS; R21 DK080351/DK/NIDDK NIH HHS
Chemical
Reg. No./Substance:
0/Pituitary Hormones
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Improvement of cardiopulmonary exercise capacity after radiofrequency ablation in patient with preex...
Next Document:  Recognizing calcific uremic arteriolopathy in autoimmune disease: an emerging mimicker of vasculitis...