Document Detail

Pituitary apoplexy: an overview of 186 cases published during the last century.
MedLine Citation:
PMID:  20140630     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Pituitary apoplexy is a rare and life-threatening complication occurring in 0.6-10.5% of all cases of pituitary adenomas. Although the association between pituitary apoplexy and visual dysfunction has been recognized for a long time, the optimal management of this problem still remains controversial. The purpose of this overview was to present the surgical experience by analyzing the literature on the management of pituitary apoplexy for better treatment of these cases. MATERIALS AND METHOD: To establish a new guideline for the surgical treatment of this entity, publications reported during the last century and databases containing medical literature were analyzed. In addition, an illustrative case with pituitary apoplexy presenting with complaints of sudden onset severe headache associated with nausea, vomiting, and a sudden loss of vision was described. In fact, the experience in our complicated patient prompted us to review the available literature on the management of pituitary apoplexy to date. CONCLUSIONS: Based on an overview of 186 cases of apoplectic pituitary adenoma presenting with monocular or binocular blindness, we highlight the importance of correct diagnosis and an early, but not necessarily emergency, surgery within the first week of admission to optimize visual outcome of such patients. The illustrative case further exemplifies the value of close interaction between members of the management team for optimal outcome.
Mehmet Turgut; Yelda Ozsunar; Sema Başak; Engin Güney; Erkin Kir; Ibrahim Meteoğlu
Publication Detail:
Type:  Case Reports; Historical Article; Journal Article; Review     Date:  2010-02-06
Journal Detail:
Title:  Acta neurochirurgica     Volume:  152     ISSN:  0942-0940     ISO Abbreviation:  Acta Neurochir (Wien)     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-19     Completed Date:  2010-07-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0151000     Medline TA:  Acta Neurochir (Wien)     Country:  Austria    
Other Details:
Languages:  eng     Pagination:  749-61     Citation Subset:  IM    
Department of Neurosurgery, Adnan Menderes University Hospital, Aydin, Turkey.
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MeSH Terms
Adenoma / complications*,  diagnosis,  surgery*
Blindness / etiology*,  physiopathology
Early Diagnosis
Endoscopy / methods
History, 20th Century
History, 21st Century
Neurosurgical Procedures / instrumentation,  methods
Optic Nerve / blood supply,  pathology,  physiopathology
Pituitary Apoplexy / complications*,  diagnosis,  surgery*
Pituitary Gland / blood supply,  pathology,  surgery
Pituitary Neoplasms / complications*,  diagnosis,  surgery*
Postoperative Complications / etiology,  pathology,  physiopathology

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