Document Detail


Pituitary-adrenal-gonadal responses to high-intensity resistance exercise overtraining.
MedLine Citation:
PMID:  9843563     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Weight-trained men [OT; n = 11; age = 22.0 +/- 0.9 (SE) yr] resistance trained daily at 100% one-repetition maximum (1-RM) intensity for 2 wk, resulting in 1-RM strength decrements and in an overtrained state. A control group (Con; n = 6; age = 23.7 +/- 2.4 yr) trained 1 day/wk at a low relative intensity (50% 1 RM). After 2 wk, the OT group exhibited slightly increased exercise-induced testosterone (preexercise = 26.5 +/- 1.3 nmol/l, postexercise = 29.1 +/- 5.9 nmol/l) and testosterone-to-cortisol ratio (preexercise = 0. 049 +/- 0.007 nmol/l, postexercise = 0.061 +/- 0.006 nmol/l) and decreased exercise-induced cortisol (preexercise = 656.1 +/- 98.1 nmol/l, postexercise = 503.1 +/- 39.7 nmol/l). Serum concentrations for growth hormone and plasma peptide F [preproenkephalin (107-140)] were similar for both groups throughout the overtraining period. This hormonal profile is distinctly different from what has been previously reported for other types of overtraining, indicating that high-relative-intensity resistance exercise overtraining may not be successfully monitered via circulating testosterone and cortisol. Unlike overtraining conditions with endurance athletes, altered resting concentrations of pituitary, adrenal, or gonadal hormones were not evident, and exercise-induced concentrations were only modestly affected.
Authors:
A C Fry; W J Kraemer; L T Ramsey
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of applied physiology (Bethesda, Md. : 1985)     Volume:  85     ISSN:  8750-7587     ISO Abbreviation:  J. Appl. Physiol.     Publication Date:  1998 Dec 
Date Detail:
Created Date:  1999-02-01     Completed Date:  1999-02-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8502536     Medline TA:  J Appl Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2352-9     Citation Subset:  IM    
Affiliation:
Human Performance Laboratories, University of Memphis, Memphis, Tennessee 38152, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Enkephalin, Methionine / analogs & derivatives,  blood
Epinephrine / blood
Exercise / physiology*
Human Growth Hormone / blood
Humans
Hydrocortisone / blood
Male
Physical Education and Training
Pituitary-Adrenal System / physiology*
Protein Precursors / blood
Testis / physiology*
Testosterone / blood
Chemical
Reg. No./Substance:
0/Protein Precursors; 12629-01-5/Human Growth Hormone; 50-23-7/Hydrocortisone; 51-43-4/Epinephrine; 58-22-0/Testosterone; 58569-55-4/Enkephalin, Methionine; 75718-92-2/peptide F

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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