Document Detail

Pituitary adenoma composed of two compartments each secreting prolactin or growth hormone.
MedLine Citation:
PMID:  3614605     Owner:  NLM     Status:  MEDLINE    
We report a case of pituitary adenoma with two compartments, i.e. a part within the sella turcica and a part infiltrating the sphenoid bone beneath the sella, producing growth hormone (GH) and prolactin. The patient had the amenorrhea-galactorrhea syndrome, but not acromegalic symptoms. Although the two compartments were united through a small dural perforation, immunohistochemical studies demonstrated that GH and prolactin were separately secreted from the intrasellar and extrasellar components, respectively. Somatotropic adenomas frequently produce prolactin, but it is unusual for these hormones to be secreted from distinctly different parts of the same lesion.
Y Tomono; T Nose; Y Maki
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Neurosurgery     Volume:  21     ISSN:  0148-396X     ISO Abbreviation:  Neurosurgery     Publication Date:  1987 Jul 
Date Detail:
Created Date:  1987-09-15     Completed Date:  1987-09-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7802914     Medline TA:  Neurosurgery     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  56-9     Citation Subset:  IM    
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MeSH Terms
Adenoma / pathology*,  surgery
Growth Hormone / secretion*
Pituitary Gland / pathology
Pituitary Neoplasms / pathology*,  surgery
Prolactin / secretion*
Reg. No./Substance:
9002-62-4/Prolactin; 9002-72-6/Growth Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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