| Pitfalls in randomized surgical trials. | |
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MedLine Citation:
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PMID: 6987765 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Special problems may arise when the principles of the randomized trial are used to compare operative methods. In the trial design that is used at present, each surgeon performs the operatons to be compared in a random order. A prerequisite for a trial so designed to result in a fair comparison is that the participating surgeons are equally conversant with both techniques. If they are not, the design may imply systematic bias in favor of operations that are in wide use and bias in favor of technically simple procedures. An alternative to this design is given. Reports on trials should contain information about pretrial routine and level of training of participants. |
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Authors:
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W van der Linden |
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Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Surgery Volume: 87 ISSN: 0039-6060 ISO Abbreviation: Surgery Publication Date: 1980 Mar |
Date Detail:
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Created Date: 1980-05-14 Completed Date: 1980-05-14 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0417347 Medline TA: Surgery Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 258-62 Citation Subset: AIM; E; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Clinical Trials as Topic Humans Random Allocation Research Design / standards* Surgical Procedures, Operative / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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