| Pitfalls in the diagnosis of immune thrombocytopenic purpura in children: 4 case reports. | |
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MedLine Citation:
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PMID: 17636197 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Acute idiopathic thrombocytopenic purpura is the most common cause of thrombocytopenia in childhood, and diagnosis of idiopathic thrombocytopenic purpura is made clinically based on the exclusion of other causes of thrombocytopenia. Patients with diverse causes of thrombocytopenia are sometimes erroneously diagnosed as having idiopathic thrombocytopenic purpura. However, for the prevention of misdiagnoses, careful inspection of peripheral blood smear is of utmost importance. This report presents 4 cases presumed as acute idiopathic thrombocytopenic purpura that were finally identified as pseudothrombocytopenia, inherited macrothrombocytopenia (MHY9 disorders) possibly Epstein syndrome, Bernard-Soulier syndrome, and drug-induced thrombocytopenia. They draw attention to the importance of platelet morphology to exclude inherited macrothrombocytopenia and history to exclude drug-induced thrombocytopenia. Better diagnostic approaches would be possible by the awareness of these relatively rare causes of isolated thrombocytopenia. |
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Authors:
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Betül Biner; Omer Devecioğlu; Muzaffer Demir |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis Volume: 13 ISSN: 1076-0296 ISO Abbreviation: Clin. Appl. Thromb. Hemost. Publication Date: 2007 Jul |
Date Detail:
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Created Date: 2007-07-19 Completed Date: 2007-09-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9508125 Medline TA: Clin Appl Thromb Hemost Country: United States |
Other Details:
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Languages: eng Pagination: 329-33 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Division of Pediatric Hematology-Oncology, School of Medicine, Trakya University, Edirne, Turkey. betulbiner2@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Antitubercular Agents / adverse effects Blood Platelets / pathology Child Female Humans Male Neutrophils / pathology Platelet Count Purpura, Thrombocytopenic, Idiopathic / chemically induced, diagnosis* |
| Chemical | |
Reg. No./Substance:
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0/Antitubercular Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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