Document Detail


Pitfalls in Doppler evaluation of diastolic function: insights from 3-dimensional magnetic resonance imaging.
MedLine Citation:
PMID:  10511650     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Ultrasound-Doppler assessment of diastolic function is subject to velocity errors caused by angle sensitivity and a fixed location of the sample volume. We used 3-dimensional phase contrast magnetic resonance imaging (MRI) to evaluate these errors in 10 patients with hypertension and in 10 healthy volunteers. The single (Doppler) and triple (MRI) component velocity was measured at early (E) and late (A) inflow along Doppler-like sample lines or 3-dimensional particle traces generated from the MRI data. Doppler measurements underestimated MRI velocities by 9.4% +/- 8.6%; the effect on the E/A ratio was larger and more variable. Measuring early and late diastolic inflows from a single line demonstrated the error caused by their 3-dimensional spatial offset. Both errors were minimized by calculating the E/A ratio from maximal E and A values without constraint to a single line. Alignment and spatial offset are important sources of error in Doppler diastolic parameters. Improved accuracy may be achieved with the use of maximal E and A velocities from wherever they occur in the left ventricle.
Authors:
A Fyrenius; L Wigström; A F Bolger; T Ebbers; K P Ohman; M Karlsson; B Wranne; J Engvall
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography     Volume:  12     ISSN:  0894-7317     ISO Abbreviation:  J Am Soc Echocardiogr     Publication Date:  1999 Oct 
Date Detail:
Created Date:  1999-11-30     Completed Date:  1999-11-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8801388     Medline TA:  J Am Soc Echocardiogr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  817-26     Citation Subset:  IM    
Affiliation:
Departments of Medicine and Care, Biomedical Engineering, Linköping University, Linköping, Sweden.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Analysis of Variance
Chi-Square Distribution
Diastole / physiology*
Echocardiography, Doppler, Color*
Female
Humans
Hypertension / physiopathology*
Image Processing, Computer-Assisted
Magnetic Resonance Imaging*
Male
Middle Aged
Myocardial Contraction

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  An integrated measure of left ventricular diastolic function based on relative rates of mitral E and...
Next Document:  Doppler-derived left ventricular rate of pressure rise determination in presence of severe acute mit...