| Pitfalls in diagnosing PFO: characteristics of false-negative contrast injections during transesophageal echocardiography in patients with patent foramen ovales. | |
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MedLine Citation:
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PMID: 20850947 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Contrast injections during transesophageal echocardiography for patent foramen ovale (PFO) detection may be false negative. The characteristics of false-negative injections were studied retrospectively. METHODS: Contrast transesophageal echocardiography was analyzed for the presence or absence of two characteristics: leftward bulging of the interatrial septum and dense contrast filling of the region of the right atrium adjacent to the interatrial septum. RESULTS: Two hundred forty-seven injections were administered to 14 patients with PFOs, and 130 (53%) were false negative. The absence of either characteristic during a single injection resulted in low sensitivity for PFO detection of 7%. When the two characteristics were present at the same time, the sensitivity for PFO detection after a single injection was as high as 95%. CONCLUSIONS: The simultaneous presence of both leftward bulging of the interatrial septum and dense contrast filling of the region in the right atrium, adjacent to the interatrial septum, is a prerequisite for PFO detection, and if either characteristic is missing, the injection is inconclusive. |
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Authors:
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Magnus C Johansson; Peter Eriksson; Cecilia Wallentin Guron; Mikael Dellborg |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't Date: 2010-09-20 |
Journal Detail:
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Title: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography Volume: 23 ISSN: 1097-6795 ISO Abbreviation: J Am Soc Echocardiogr Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-10-26 Completed Date: 2011-02-17 Revised Date: 2011-03-28 |
Medline Journal Info:
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Nlm Unique ID: 8801388 Medline TA: J Am Soc Echocardiogr Country: United States |
Other Details:
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Languages: eng Pagination: 1136-42 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 American Society of Echocardiography. Published by Mosby, Inc. All rights reserved. |
Affiliation:
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Department of Emergency and Cardiovascular Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. magnus.c.johansson@vgregion.se |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Analysis of Variance Cohort Studies Contrast Media / diagnostic use* Echocardiography, Transesophageal / adverse effects, methods* False Negative Reactions Female Foramen Ovale, Patent / ultrasonography* Humans Image Enhancement* Injections, Intravenous Male Middle Aged Polygeline / diagnostic use* Reference Values Severity of Illness Index |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 9015-56-9/Polygeline |
| Comments/Corrections | |
Comment In:
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J Am Soc Echocardiogr. 2011 Mar;24(3):348; author reply 348-9
[PMID:
21227648
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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