| Pirprofen in acute ocular inflammation: a controlled study. | |
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MedLine Citation:
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PMID: 3907989 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In a double-blind, between-patient trial, 30 patients affected by acute ocular inflammation were treated with either pirprofen capsules (400 mg twice daily) or indomethacin capsules (50 mg twice daily) for 14 days. Treatment efficacy was evaluated in basal conditions and after 3, 6, 10 and 14 days on the basis of the following criteria: keratic injection, Tyndall phenomenon, vitreous changes, endothelial precipitates and pain severity, all according to 4-point scales. At the end of the study, a final judgement was expressed by the physician. Non-parametric statistical tests showed that both treatments significantly modified all the parameters considered. Both drugs were well tolerated; only 1 patient on pirprofen dropped out because of gastralgia. |
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Authors:
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F Saggio; V Maresca; G C Monza |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Current medical research and opinion Volume: 9 ISSN: 0300-7995 ISO Abbreviation: Curr Med Res Opin Publication Date: 1985 |
Date Detail:
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Created Date: 1986-02-20 Completed Date: 1986-02-20 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0351014 Medline TA: Curr Med Res Opin Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 697-700 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Anti-Inflammatory Agents, Non-Steroidal / therapeutic use* Clinical Trials as Topic Double-Blind Method Female Humans Indomethacin / therapeutic use Keratitis, Dendritic / drug therapy* Male Middle Aged Phenylpropionates / therapeutic use* Random Allocation Time Factors Uveitis, Anterior / drug therapy* |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents, Non-Steroidal; 0/Phenylpropionates; 31793-07-4/pirprofen; 53-86-1/Indomethacin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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