Document Detail

Pirprofen in acute ocular inflammation: a controlled study.
MedLine Citation:
PMID:  3907989     Owner:  NLM     Status:  MEDLINE    
In a double-blind, between-patient trial, 30 patients affected by acute ocular inflammation were treated with either pirprofen capsules (400 mg twice daily) or indomethacin capsules (50 mg twice daily) for 14 days. Treatment efficacy was evaluated in basal conditions and after 3, 6, 10 and 14 days on the basis of the following criteria: keratic injection, Tyndall phenomenon, vitreous changes, endothelial precipitates and pain severity, all according to 4-point scales. At the end of the study, a final judgement was expressed by the physician. Non-parametric statistical tests showed that both treatments significantly modified all the parameters considered. Both drugs were well tolerated; only 1 patient on pirprofen dropped out because of gastralgia.
F Saggio; V Maresca; G C Monza
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Current medical research and opinion     Volume:  9     ISSN:  0300-7995     ISO Abbreviation:  Curr Med Res Opin     Publication Date:  1985  
Date Detail:
Created Date:  1986-02-20     Completed Date:  1986-02-20     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0351014     Medline TA:  Curr Med Res Opin     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  697-700     Citation Subset:  IM    
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MeSH Terms
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
Clinical Trials as Topic
Double-Blind Method
Indomethacin / therapeutic use
Keratitis, Dendritic / drug therapy*
Middle Aged
Phenylpropionates / therapeutic use*
Random Allocation
Time Factors
Uveitis, Anterior / drug therapy*
Reg. No./Substance:
0/Anti-Inflammatory Agents, Non-Steroidal; 0/Phenylpropionates; 31793-07-4/pirprofen; 53-86-1/Indomethacin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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