| Pipecolic acid levels in serum and urine from neonates and normal infants: comparison with values reported in Zellweger syndrome. | |
| | |
MedLine Citation:
|
PMID: 3939538 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Pipecolic acid (PA) excretion from normal newborn, preterm and/or small-for-dates infants has been determined and correlated with gestational age, sex and age after birth. An effect of fetal sex was not detectable. Only small-for-dates infants with a gestational age of greater than 34-37 weeks had a lower urinary excretion of PA than the appropriate-for-dates infants with the same gestational age. Preterm infants had a higher excretion of PA than term neonates. PA excretion of infants decreases with age after birth. This higher excretion in "younger" infants can be explained by a higher serum concentration and less efficient tubular reabsorption. PA level in serum and urine remains a valuable tool for the confirmation of the clinical diagnosis of Zellweger syndrome when gestational age and age after birth are taken into consideration. No PA was detected in serum or urine of four children suffering from hyperthyroidism. |
| | |
Authors:
|
L Govaerts; F Trijbels; L Monnens; A van Raay-Selten |
Related Documents
:
|
4000768 - Hypouricemia in neonates with syndrome of inappropriate secretion of antidiuretic hormone. 7136618 - Interrelation between fatty acid oxidation and control of gluconeogenic substrates in s... 6810478 - Effect of a new neonatal maintenance solution on potassium, calcium and phosphate homeo... 23401418 - Increased lung volume in infants and toddlers at high compared to low altitude. 1514108 - Retinol (vitamin a) and riboflavin (vitamin b2) administration and metabolism in very l... 23265618 - Ultrasound-guided neuronavigation improves safety of ventricular catheter insertion in ... |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: Journal of inherited metabolic disease Volume: 8 ISSN: 0141-8955 ISO Abbreviation: J. Inherit. Metab. Dis. Publication Date: 1985 |
Date Detail:
|
Created Date: 1987-01-09 Completed Date: 1987-01-09 Revised Date: 2007-03-21 |
Medline Journal Info:
|
Nlm Unique ID: 7910918 Medline TA: J Inherit Metab Dis Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 87-91 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Female Genes, Recessive* Hepatomegaly / metabolism* Humans Hyperthyroidism / metabolism Infant, Newborn Infant, Premature Infant, Small for Gestational Age Male Muscle Hypotonia / metabolism* Pipecolic Acids / analysis* Polycystic Kidney Diseases / metabolism* Reference Values Syndrome |
| Chemical | |
Reg. No./Substance:
|
0/Pipecolic Acids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Diagnosis of classical Morquio's disease: N-acetylgalactosamine 6-sulphate sulphatase activity in cu...
Next Document: Dolichol and phosphorylated dolichol content of tissues in ceroid-lipofuscinosis.