Document Detail

Pinnarine, Another Member of the Halichlorine Family. Isolation and Preparation from Pinnaic Acid.
MedLine Citation:
PMID:  21410164     Owner:  NLM     Status:  Publisher    
Pinnarine (1), a new macrocyclic alkaloid, was isolated from the black marine sponge Halichondria okadai. The structure was elucidated on the basis of 2D NMR and comparison with the spectra of the co-isolated known halichlorine. Further confirmation of the structure and the absolute configuration was validated by a synthetic method from authentic pinnaic acid and CD analysis. The isolation of pinnarine also suggested a biogenetic pathway from pinnaic acid to halichlorine.
Shu Xu; Hideaki Yoshimura; Norihito Maru; Osamu Ohno; Hirokazu Arimoto; Daisuke Uemura
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-16
Journal Detail:
Title:  Journal of natural products     Volume:  -     ISSN:  1520-6025     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-3-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7906882     Medline TA:  J Nat Prod     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Chemistry, Graduate School of Science, Nagoya University , Furo-cho, Chikusa, Nagoya 464-8602, Japan.
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