| Pine resin and biopin ointment: effects of water-soluble fractions on cytokine production by peripheral blood neutrophils. | |
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MedLine Citation:
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PMID: 12459838 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We studied the effects of water-soluble fractions of pine resin and Biopin-10 and Biopin-20 ointments used for the therapy of burns, wounds, and purulent and inflammatory diseases on spontaneous and induced synthesis of tumor necrosis factor and interleukins 1, 2, and 8 by human peripheral blood neutrophils in vitro. These preparations contain various bioactive substances producing opposite and dose-dependent immunomodulatory effects. Our results indicate that the composition and doses of preparations should be selected to achieve the maximum therapeutic effect. |
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Authors:
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A S Simbirtsev; V G Konusova; G Sh McHedlidze; B A Paramonov; V Yu Chebotarev |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Bulletin of experimental biology and medicine Volume: 134 ISSN: 0007-4888 ISO Abbreviation: Bull. Exp. Biol. Med. Publication Date: 2002 Aug |
Date Detail:
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Created Date: 2002-12-02 Completed Date: 2003-07-16 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372557 Medline TA: Bull Exp Biol Med Country: United States |
Other Details:
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Languages: eng Pagination: 151-5 Citation Subset: IM |
Affiliation:
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Institute of High-Purity Biological Preparations, St. Petersburg. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Biopterin
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administration & dosage,
pharmacology* Humans Interleukins / biosynthesis* Neutrophils / drug effects*, metabolism Ointments* Resins, Plant / administration & dosage, pharmacology* Tumor Necrosis Factor-alpha / biosynthesis* |
| Chemical | |
Reg. No./Substance:
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0/Interleukins; 0/Ointments; 0/Resins, Plant; 0/Tumor Necrosis Factor-alpha; 22150-76-1/Biopterin; 8050-09-7/rosin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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