| Pimozide and p-chlorophenylalanine blockade in DL-amphetamine and pargyline-treated rats held at two environmental temperatures. | |
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MedLine Citation:
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PMID: 158537 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In rats, treated with DL-amphetamine + monoamine oxidase inhibitor, and held at an ambient temperature of 28.5 degrees C, hyperthermia was completely eliminated by treatment with pimozide + p-chlorophenyl-alanine. The same drugs markedly reduced the hypothermic effects in rats treated similarly at 4 degrees C. Results implied that serotoninergic and dopaminergic neurones were involved in the thermoregulatory effects of amphetamine. |
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Authors:
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B A Panaretto |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Experientia Volume: 35 ISSN: 0014-4754 ISO Abbreviation: Experientia Publication Date: 1979 Sep |
Date Detail:
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Created Date: 1979-12-29 Completed Date: 1979-12-29 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0376547 Medline TA: Experientia Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 1223-4 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amphetamines
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pharmacology* Animals Body Temperature / drug effects* Fenclonine / pharmacology* Fever / physiopathology* Male Pargyline / pharmacology* Pimozide / pharmacology* Rats Temperature |
| Chemical | |
Reg. No./Substance:
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0/Amphetamines; 2062-78-4/Pimozide; 555-57-7/Pargyline; 7424-00-2/Fenclonine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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