Document Detail

Pimozide attenuates acquisition of lever-pressing for food in rats.
MedLine Citation:
PMID:  7291269     Owner:  NLM     Status:  MEDLINE    
Pimozide pretreatment produced a dose-dependent attenuation of acquisition of a lever-pressing habit motivated by food reward in hungry rats. No evidence of learning was seen in animals treated at 1.0 mg/kg, minimal learning was seen at 0.5 mg/kg, and retarded learning which ultimately did reach normal asymptote was seen at 0.25 mg/kg. Thus primozide attenuates the response acquisition function as well as the previously studied response maintenance function of food reward.
R A Wise; H V Schwartz
Related Documents :
19014269 - Quality before quantity: rapid learning of reverse-reward contingency by capuchin monke...
20708659 - Dogs choose a human informant: metacognition in canines.
25242619 - Development and evaluation of the us healthy food diversity index.
16129239 - Time-place learning in the cichlid angelfish, pterophyllum scalare.
12044689 - A simple spatial alternation task for assessing memory function in zebrafish.
2924529 - Numerical competence in a chimpanzee (pan troglodytes).
8154469 - Dietary glutathione intake and the risk of oral and pharyngeal cancer.
17719109 - Measurement of aggregation properties between probiotics and pathogens: in vitro evalua...
21630319 - Re-establishment of biting mouthparts in desert-living dung beetles (scarabaeidae: scar...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pharmacology, biochemistry, and behavior     Volume:  15     ISSN:  0091-3057     ISO Abbreviation:  Pharmacol. Biochem. Behav.     Publication Date:  1981 Oct 
Date Detail:
Created Date:  1981-12-22     Completed Date:  1981-12-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0367050     Medline TA:  Pharmacol Biochem Behav     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  655-6     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Conditioning, Operant / drug effects*
Depression, Chemical
Pimozide / pharmacology*
Rats, Inbred Strains
Receptors, Dopamine / drug effects
Reg. No./Substance:
0/Receptors, Dopamine; 2062-78-4/Pimozide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Morphine conditioned taste aversion reversed by periaqueductal gray lesions.
Next Document:  Antagonism of the behavioral effects of 2,5-dimethoxy-4-methylamphetamine (DOM) and quipazine by met...