Document Detail

Pilot study of the systemic effects of three different screening methods used for retinopathy of prematurity.
MedLine Citation:
PMID:  15814220     Owner:  NLM     Status:  MEDLINE    
PURPOSE: This pilot study compared the physiological and behavioural changes in premature infants undergoing three different methods of screening for retinopathy of prematurity (ROP). STUDY DESIGN: Prospective randomized cross-over pilot study. SUBJECTS AND METHODS: Fifteen premature infants requiring screening for ROP were recruited, and physiological and behavioural responses produced by three different methods of screening were compared. The screening methods employed a RetCam 120 and an indirect ophthalmoscope with and without an eyelid speculum. Physiological indices (change in pulse, mean blood pressure and oxygen saturation) and facial responses to pain (brow bulge, eye squeeze, nasolabial fold, mouth opening and the presence of cry) were recorded at five points: before, during and immediately after screening and 10 and 30 min after examination. RESULTS: Screening with the RetCam 120 and the indirect ophthalmoscope with a speculum both caused a greater change in pulse and mean blood pressure and an increase in facial responses to pain during and immediately after screening as compared to the indirect ophthalmoscope without the speculum. RetCam 120 screening caused greater desaturation than the other methods. CONCLUSIONS: Although this was a small sample which limits absolute conclusions, the study showed that screening using a RetCam or a speculum and indirect ophthalmoscope caused more stress to the infant, as indicated by physiological and behavioural changes, than simply screening using an indirect ophthalmoscope without a speculum. These effects should be considered when deciding on the appropriate screening method for examining particularly sick infants.
Manisha Mehta; G G W Adams; Catey Bunce; Wen Xing; Mercy Hill
Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial     Date:  2004-12-08
Journal Detail:
Title:  Early human development     Volume:  81     ISSN:  0378-3782     ISO Abbreviation:  Early Hum. Dev.     Publication Date:  2005 Apr 
Date Detail:
Created Date:  2005-04-07     Completed Date:  2005-06-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7708381     Medline TA:  Early Hum Dev     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  355-60     Citation Subset:  IM    
Strabismus and Paediatric Service, Moorfields Eye Hospital, 162 City Road, London EC1V 2PD, UK.
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MeSH Terms
Gestational Age
Infant Behavior
Infant, Newborn
Infant, Premature
Pilot Projects
Prospective Studies
Retinopathy of Prematurity / diagnosis*
Retinoscopy / methods*
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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