Document Detail

Pilot study of a novel mandibular advancement device for the control of snoring.
MedLine Citation:
PMID:  15267184     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Mandibular advancement devices (MADs) have been introduced as a conservative, non-invasive treatment for socially disturbing snoring and mild obstructive sleep apnea (OSA). A prospective, non-randomized pilot study was conducted to investigate the efficacy, feasibility, side-effects and compliance of Somnoguard, an immediately intraorally adaptable MAD made from thermoplastic material. MATERIAL AND METHODS: Twenty consecutive heavy snorers with a respiratory disturbance index of <20 events/h were prospectively selected. Prior to the adaptation of the appliance, ambulatory polygraphy was carried out without a MAD. After a 1-month habituation period, a polygraphic evaluation was carried out with the device. Treatment success was defined as a reduction in the apnea-hypopnea index (AHI) of at least 50%. RESULTS: The results indicated a success rate of 65%. The AHI decreased from 8.4 +/- 2.9 events/h at baseline to 3.9 +/- 1.8 events/h with the device (p = 0.001). At 1-month follow-up, significant reductions in the snoring index (p < 0.001) and the Epworth Sleepiness Scale (ESS) score (p = 0.036) were noted. At 6-month follow-up, similar results were achieved, with significant drops in the snoring index (p = 0.025) and ESS score (p = 0.033). CONCLUSION: We conclude that immediate intraoral adaptation of a low-cost fabricated "one-size-only" MAD is a feasible and well-tolerated treatment for snoring and mild OSA. Further research is needed to evaluate this thermoplastic appliance as a strategy to "screen" the efficacy of MAD treatment in the individual patient with a less expensive appliance before constructing a more expensive custom-made MAD.
Olivier M Vanderveken; An N Boudewyns; Marc J Braem; Walter Okkerse; Johan A Verbraecken; Marc Willemen; Floris L Wuyts; Wilfried A De Backer; Paul H Van de Heyning
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Acta oto-laryngologica     Volume:  124     ISSN:  0001-6489     ISO Abbreviation:  Acta Otolaryngol.     Publication Date:  2004 Jun 
Date Detail:
Created Date:  2004-07-22     Completed Date:  2005-02-15     Revised Date:  2005-04-13    
Medline Journal Info:
Nlm Unique ID:  0370354     Medline TA:  Acta Otolaryngol     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  628-33     Citation Subset:  IM    
Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital, University of Antwerp, Antwerp, Belgium.
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MeSH Terms
Equipment Design
Mandibular Advancement / instrumentation*
Middle Aged
Patient Compliance
Patient Satisfaction
Pilot Projects
Prospective Studies
Snoring / therapy*
Treatment Outcome
Reg. No./Substance:

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