| Pilot study evaluating technical feasibility and early outcomes of second-generation endosurgical platform for treatment of weight regain after gastric bypass surgery. | |
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MedLine Citation:
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PMID: 19632645 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: For some gastric bypass patients, dilation of the gastrojejunal anastomosis (GJA) and/or gastric pouch is believed to contribute to weight regain. The present study had 2 objectives: (1) to assess the technical feasibility and safety of a novel endoscopic procedure called "revision obesity surgery endoscopic" (ROSE) using a second-generation, prototype endoscopic operating system that creates tissue plications to reduce the diameter of the GJA and the size of the gastric pouch; and (2) to assess the early outcomes regarding weight loss at a university hospital in the United States. METHODS: This was a prospective study of 5 patients who had regained a mean of 14.7 kg after gastric bypass with a dilated pouch and GJA on screening endoscopy. The gastric pouch and the GJA were measured before and after the procedure. The patients were followed up for a minimum of 3 months after the procedure. Weight changes were recorded. RESULTS: Technical success was achieved in all 5 patients (100%). The mean weight loss in the successful cases was 7.8 kg at 3 months. No major complications developed. CONCLUSION: The results of our study have shown that the ROSE procedure using this second-generation prototype endoscopic operating system is technically feasible and appears safe. Our preliminary results suggest that the ROSE procedure is effective in reducing the size of both the GJA and the gastric pouch and could therefore be an alternative therapy for weight regain in postgastric bypass patients. |
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Authors:
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Marvin Ryou; Daniel K Mullady; David B Lautz; Christopher C Thompson |
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Publication Detail:
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Type: Clinical Trial; Journal Article Date: 2009-04-08 |
Journal Detail:
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Title: Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery Volume: 5 ISSN: 1878-7533 ISO Abbreviation: - Publication Date: 2009 Jul-Aug |
Date Detail:
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Created Date: 2009-07-27 Completed Date: 2009-11-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101233161 Medline TA: Surg Obes Relat Dis Country: United States |
Other Details:
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Languages: eng Pagination: 450-4 Citation Subset: IM |
Affiliation:
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Division of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Endoscopes* Endoscopy* Feasibility Studies Female Follow-Up Studies Gastric Bypass / instrumentation* Humans Middle Aged Obesity / surgery* Pilot Projects Reoperation Suture Techniques / instrumentation* Treatment Failure Weight Gain |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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