| Pilot study of new diagnostic criteria for middle cerebral artery stenosis by transcranial Doppler. | |
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MedLine Citation:
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PMID: 19187479 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND AND PURPOSE: Current criteria for middle cerebral artery (MCA) stenosis by transcranial Doppler were mainly based on the flow velocity acceleration, ignoring other useful parameters. We tested the accuracy of new criteria using magnetic resonance angiography (MRA) as the confirmative method. METHODS: A compositive score for each MCA was calculated according to following parameters: Velocity Scale (score 0-6 for peak systolic velocity <140 to > or = 300 cm/second), Hemodynamic Scale (score 0-5 for diffuse or focal velocity increase; score 0-6 for differences between bilateral MCA; score 17 for damping velocity), and Spectrum Scale (score 0-2 for normal spectrum, turbulence, and musical murmurs). RESULTS: The median scores in normal-mild, moderate, and severe groups on MRA differed significantly (P < .001). The optimal cutoff score for <50% and > or = 50% stenosis was 3 with the PPV of 72.3% (95% confidence interval [CI]: 65.3% to 78.5%) and negative predictive value (NPV) of 89.5% (95% CI: 85.9% to 92.3%), for moderate and severe stenosis was 6 with the PPV of 85.9% (95% CI: 76.7% to 92.0%) and NPV of 61.9% (95% CI: 50.6% to 72.1%). Both scores performed better than peak systolic or mean velocity. CONCLUSIONS: This new method was feasible and reliable and showed some advantages over the velocity-only method. Further studies using digital subtraction angiography as the gold standard are needed to ameliorate the new criteria. |
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Authors:
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Qing Hao; Shan Gao; Thomas Wai Hong Leung; Ming Hui Guo; Yong You; Ka Sing Wong |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-01-29 |
Journal Detail:
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Title: Journal of neuroimaging : official journal of the American Society of Neuroimaging Volume: 20 ISSN: 1552-6569 ISO Abbreviation: J Neuroimaging Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-05-21 Completed Date: 2010-09-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9102705 Medline TA: J Neuroimaging Country: United States |
Other Details:
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Languages: eng Pagination: 122-9 Citation Subset: IM |
Affiliation:
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Department of Medicine &Therapeutics, The Chinese University of Hong Kong, Hong Kong, China. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Algorithms* Female Humans Image Enhancement / methods Image Interpretation, Computer-Assisted / methods* Infarction, Middle Cerebral Artery / ultrasonography* Male Middle Aged Pilot Projects Reproducibility of Results Sensitivity and Specificity Ultrasonography, Doppler, Transcranial / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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