Document Detail

A pilot study of comparison of BCPAP vs. VCPAP in preterm infants with early onset respiratory distress.
MedLine Citation:
PMID:  19843596     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Bubble continuous positive airway pressure (BCPAP) is a low-cost nasal CPAP delivery system with potential benefits for developing nations. The objective of the study was to compare the efficacy and safety of BCPAP with ventilator CPAP (VCPAP) in preterm neonates with moderate respiratory distress. METHODS: In a pilot randomized controlled trial, 30 preterm neonates (gestation <37 weeks) with Silverman-Anderson score between 5 to 7 and oxygen requirement >30% within first 6 h of life were randomly allocated to BCPAP or VCPAP after informed parental consent. Proportion of neonates with success or failure, while using the allocated mode of CPAP delivery (primary outcome) was compared. RESULTS: The success rate was comparable [VCPAP: 80% (12/15) vs. BCPAP: 87% (13/15)] between the two groups. Dislodgement was commonest problem with equal frequency [10/15, (67%)] in each group. CONCLUSION: BCPAP appears to be a promising method of CPAP delivery in preterm neonates with moderate respiratory distress.
Amit Tagare; Sandeep Kadam; Umesh Vaidya; Anand Pandit; Sanjay Patole
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial     Date:  2009-10-20
Journal Detail:
Title:  Journal of tropical pediatrics     Volume:  56     ISSN:  1465-3664     ISO Abbreviation:  J. Trop. Pediatr.     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-27     Completed Date:  2010-07-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8010948     Medline TA:  J Trop Pediatr     Country:  England    
Other Details:
Languages:  eng     Pagination:  191-4     Citation Subset:  IM    
Division of Neonatology, Department of Pediatrics, KEM Hospital, Rasta Peth, Pune 411011, India.
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MeSH Terms
Continuous Positive Airway Pressure / instrumentation*,  methods*
Gestational Age
Infant, Newborn
Infant, Premature*
Infant, Premature, Diseases / epidemiology
Intensive Care, Neonatal / methods
Pilot Projects
Respiratory Distress Syndrome, Newborn / epidemiology,  therapy*
Respiratory Insufficiency / epidemiology,  therapy*
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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