Document Detail

Pilonidal sinus excision--healing by open granulation.
MedLine Citation:
PMID:  4027539     Owner:  NLM     Status:  MEDLINE    
A prospective study is reported of 100 pilonidal sinus excisions healing by open granulation. Delays in healing appeared to be due to infection, particularly by anaerobic bacteria. Comparisons are made between three groups studied consecutively - 30 wounds not treated with antibiotics, 20 given a fixed two-week course of metronidazole and 50 managed flexibly. In this last group, wound management was determined by clinical appearance; 24 wounds were clinically healthy throughout and received no antibiotic while 26 looked unhealthy initially or after an interval and were treated with metronidazole, supplemented in some cases with erythromycin. The best results were obtained in the group managed flexibly. It is considered that the problems of delayed healing are due to excisions which leave a wound of a shape ill-designed to maintain good drainage. Unhealthy wounds should be re-shaped if possible and treated early with a combination of metronidazole and erythromycin.
J Marks; K G Harding; L E Hughes; C D Ribeiro
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The British journal of surgery     Volume:  72     ISSN:  0007-1323     ISO Abbreviation:  Br J Surg     Publication Date:  1985 Aug 
Date Detail:
Created Date:  1985-10-09     Completed Date:  1985-10-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372553     Medline TA:  Br J Surg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  637-40     Citation Subset:  AIM; IM    
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MeSH Terms
Bacteria, Anaerobic / isolation & purification
Erythromycin / therapeutic use
Granulation Tissue
Metronidazole / therapeutic use
Pilonidal Sinus / surgery*
Prospective Studies
Surgical Wound Infection / drug therapy,  microbiology
Time Factors
Wound Healing*
Reg. No./Substance:
114-07-8/Erythromycin; 443-48-1/Metronidazole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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