| Pilomatrix carcinoma with multiple metastases: report of a case and review of the literature. | |
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MedLine Citation:
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PMID: 10448295 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pilomatrix carcinoma, the malignant counterpart of pilomatrixoma, is rare, with only 55 cases reported, and only four cases with visceral metastases described in the literature. Here we present a case report and a literature review on this rare tumour. A 74-year-old male with a pilomatrix carcinoma from the left temporal region presented in July 1996 and the tumour was excised. One month after diagnosis, metastases to both lungs and to a regional lymph node were found and histologically verified. The patient also developed metastases in the abdomen, back and thoracic spine. The latter resulted in spinal cord compression and paraplegia. Despite systemic chemotherapy with intravenous cisplatin and 5-fluorouracil and localised radiotherapy to the thoracic spine, progression and deterioration led to death within 3 months from time of diagnosis. Pilomatrix carcinomas are usually indolent. In our patient, however, the malignant disease progressed rapidly and it appeared to be resistant to both chemotherapy and irradiation. |
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Authors:
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R M Bremnes; J M Kvamme; H Stalsberg; E A Jacobsen |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: European journal of cancer (Oxford, England : 1990) Volume: 35 ISSN: 0959-8049 ISO Abbreviation: Eur. J. Cancer Publication Date: 1999 Mar |
Date Detail:
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Created Date: 1999-08-23 Completed Date: 1999-08-23 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9005373 Medline TA: Eur J Cancer Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 433-7 Citation Subset: IM |
Affiliation:
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Department of Oncology, University Hospital of Tromsø, Norway. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abdominal Neoplasms
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secondary* Aged Fatal Outcome Hair Diseases / pathology* Humans Lung Neoplasms / secondary* Magnetic Resonance Imaging Male Pilomatrixoma / secondary*, therapy Skin Neoplasms / pathology*, therapy Spinal Neoplasms / secondary* Tomography, X-Ray Computed |
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