Document Detail

Pigmented mesenteric lymphadenopathy in familial adenomatous polyposis - an unusual cause of intraoperative abandonment of ileo-anal pouch.
MedLine Citation:
PMID:  16884599     Owner:  NLM     Status:  MEDLINE    
Familial adenomatous polyposis (FAP) is an autosomal dominant condition with near complete penetrance, characterised by the presence of numerous adenomatous polyps of the colon and rectum. Melanosis coli describes the brownish-black discolouration of the colon resulting from the accumulation of a granular pigment in the phagosomes of macrophages in the colonic lamina propria. The presence of melanosis pigment in pericolonic lymph nodes has been reported in patients with coincidental melanosis coli, following segmental colonic resection. We report a unique case of FAP with melanosis pigment in lymph nodes in the small bowel mesentery that initially prevented a restorative proctocolectomy but that resolved following a colectomy, subsequently facilitating formation of an ileo-anal pouch.
N Pranesh; N Y Haboubi; S T O'Dwyer
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of the Royal College of Surgeons of England     Volume:  87     ISSN:  0035-8843     ISO Abbreviation:  Ann R Coll Surg Engl     Publication Date:  2005 Jul 
Date Detail:
Created Date:  2006-08-03     Completed Date:  2006-08-18     Revised Date:  2008-11-20    
Medline Journal Info:
Nlm Unique ID:  7506860     Medline TA:  Ann R Coll Surg Engl     Country:  England    
Other Details:
Languages:  eng     Pagination:  W1-4     Citation Subset:  IM    
Department of Surgery, Christie Hospital, Manchester, UK.
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MeSH Terms
Adenomatous Polyposis Coli / complications,  surgery*
Colonic Pouches
Intraoperative Complications / etiology
Lymphatic Diseases / complications*,  pathology
Melanosis / complications*,  pathology
Peritoneal Diseases / complications*
Proctocolectomy, Restorative

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