Document Detail

Pigmented and hyperkeratotic napkin dermatitis: a liquid detergent irritant dermatitis.
MedLine Citation:
PMID:  8864616     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Napkin or diaper dermatitis (DD) is an inflammatory cutaneous eruption limited to the diaper area and common in the first 2 years of life. A number of clinical variants of DD have been identified. OBJECTIVE: We report a new variant of DD characterized by papyraceous skin, brownish discoloration and predilection for the depth of folds. METHODS: 15 infants and toddlers affected by this peculiar type of DD were evaluated regarding duration, localization, morphology and evolution of their dermatosis. RESULTS: This variant of DD was mainly confined to the depth of inguinal and gluteal folds and invariably associated with severe xerosis with papyraceous and glazed skin. The patients were healthy and asymptomatic and all laboratory investigations performed were normal. All patients were frequently changed and thoroughly washed with synthetic detergents with acid pH. DD improved rapidly with reduced frequency of washing and discontinuation of liquid detergents. CONCLUSIONS: We conclude that this condition is a type of irritant contact dermatitis from excessive use of lipid acid detergents.
A Patrizi; I Neri; S Marzaduri; L Fiorillo
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Dermatology (Basel, Switzerland)     Volume:  193     ISSN:  1018-8665     ISO Abbreviation:  Dermatology (Basel)     Publication Date:  1996  
Date Detail:
Created Date:  1997-01-16     Completed Date:  1997-01-16     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9203244     Medline TA:  Dermatology     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  36-40     Citation Subset:  IM    
Department of Dermatology, University of Bologna, Italy.
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MeSH Terms
Dermatitis, Irritant / diagnosis,  pathology*,  physiopathology,  therapy
Detergents / adverse effects*
Diaper Rash / diagnosis,  drug therapy,  pathology*,  physiopathology
Reg. No./Substance:

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