Document Detail

Pigmented free-floating vitreous cysts in two young adults. Electron microscopic observations.
MedLine Citation:
PMID:  3982808     Owner:  NLM     Status:  MEDLINE    
Pigmented free-floating vitreous cysts were observed in two young adults. In both patients, the cyst was in the visual axis; however, the size and extent of pigmentation of the cyst wall compromised the visual acuity only in case 1. In this case, the vitreous cyst was aspirated through the pars plana and studied by light and electron microscopy. Histopathologically, the cyst was lined by a heavily pigmented layer of cuboidal cells intermixed with sheets of nonpigmented cells forming papillae. Ultrastructurally, the pigmented cells contained predominantly large, mature melanosomes (0.9-2.2 micron). Scattered immature melanosomes with a scarcity of mitochondria and other cytoplasmic organelles were present. Additionally, the cells were invested by a thin polarized basement membrane and displayed apical microvilli. Numerous microvillous processes were noted under the plasmalemmae and between adjacent cells. The results of the light and ultrastructural studies provide support for the hypothesis that the cyst in case 1 originated from the pigment epithelium. The possibility of a traumatic etiology is proposed for these pigmented vitreous cysts. If significant visual impairment is present, surgical removal of the cyst through a pars plana approach can be safely performed as in our case 1.
J Orellana; R E O'Malley; A R McPherson; R L Font
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Ophthalmology     Volume:  92     ISSN:  0161-6420     ISO Abbreviation:  Ophthalmology     Publication Date:  1985 Feb 
Date Detail:
Created Date:  1985-05-20     Completed Date:  1985-05-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7802443     Medline TA:  Ophthalmology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  297-302     Citation Subset:  IM    
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MeSH Terms
Cysts / pathology*
Eye Diseases / pathology
Microscopy, Electron
Vitreous Body / pathology*

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