Document Detail

Pigmentation development, defects, and patterning in summer flounder (Paralichthys dentatus).
MedLine Citation:
PMID:  16351966     Owner:  NLM     Status:  MEDLINE    
Flounders offer unique opportunities to study the cytological basis of vertebrate pigmentation. Individual skin pigment cells are clearly visible at hatching, and flounder ontogeny includes a dramatic shift in overall pigmentation (from symmetrical to asymmetrical) during metamorphosis. Moreover, several types of malpigmentation occur in hatchery populations; although much effort has gone into reducing the frequency of such defects, their etiology remains poorly understood, and they have rarely been described at the cellular level. In this paper, we use light and fluorescence microscopy to describe the cytological basis of normal developmental changes and of common types of malpigmentation. We then discuss the implications of these observations for underlying patterning mechanisms.
Jessica A Bolker; Tanya F Hakala; Judith E Quist
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2005-07-19
Journal Detail:
Title:  Zoology (Jena, Germany)     Volume:  108     ISSN:  0944-2006     ISO Abbreviation:  Zoology (Jena)     Publication Date:  2005  
Date Detail:
Created Date:  2005-12-14     Completed Date:  2006-06-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9435608     Medline TA:  Zoology (Jena)     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  183-93     Citation Subset:  IM    
Department of Zoology, University of New Hampshire, 216 Rudman Hall, Durham, NH 03824, USA.
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MeSH Terms
Aminobenzoic Acids / toxicity
Anesthetics / toxicity
Fish Diseases / pathology*
Formaldehyde / toxicity
Melanophores / drug effects,  pathology,  physiology
Microscopy, Fluorescence
Pigmentation / physiology*
Pigmentation Disorders / pathology,  veterinary*
Skin / pathology*
Reg. No./Substance:
0/Aminobenzoic Acids; 0/Anesthetics; 50-00-0/Formaldehyde; 582-33-2/tricaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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