| Phytoestrogens enhance antioxidant enzymes after swimming exercise and modulate sex hormone plasma levels in female swimmers. | |
| | |
MedLine Citation:
|
PMID: 21331628 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Our aim was to investigate the effects of diet supplementation with phytoestrogens on sex hormone levels, antioxidant adaptive responses and oxidative damage induced by exercise. Ten female swimmers participated for 26 days in a diet intervention with either a functional beverage rich in vitamins C and E or the same beverage but also supplemented with Lippia citriodora extract (PLX) containing 20 mg/100 ml verbascoside. After the intervention all subjects participated in a swimming session for 30 min maintaining the intensity at about 75-80% of their individual best performance time for a 50-m swim. In lymphocytes, the superoxide dismutase activity increased after exercise, with a higher increase in the PLX group. Swimming increased the erythrocyte activity of glutathione peroxidase and glutathione reductase in the PLX group. Purified glutathione reductase activity increased after an in vitro incubation with PLX. No effects were observed on the lymphocyte levels of malondialdehyde and carbonyls, but exercise increased the percentage of high-damaged lymphocytes 2.8 times in the placebo group and 1.5 times in the PLX group. PLX decreased the levels of 17-β-estradiol and testosterone and increased the levels of the sex hormone binding globulin. In conclusion, supplementation with phytoestrogens enhances the glutathione-dependent enzyme activities in erythrocytes and the superoxide dismutase activity in lymphocytes in response to exercise. PLX also shows direct antioxidant properties, by increasing glutathione reductase enzyme activity in vitro. Supplementation with phytoestrogens also decreases the plasma steroid hormone levels, pointing towards a possible agonistic effect of verbascoside in the hypothalamic regulation of estradiol synthesis. |
| | |
Authors:
|
Antonia Mestre-Alfaro; Miguel D Ferrer; Antoni Sureda; Pedro Tauler; Elisa Martínez; Maria M Bibiloni; Vicente Micol; Josep A Tur; Antoni Pons |
Related Documents
:
|
11978928 - Migratory pulmonary infiltrates in a patient with rheumatoid arthritis. 11029358 - Role of co diffusing capacity during exercise in the preoperative evaluation for lung r... 21273898 - Exercise paradigms to study brain injury recovery in rodents. 2651388 - Effects of lung volume, volume history, and methacholine on lung tissue viscance. 6930878 - Evaluation of cardiac function in patients with thalassemia major. 708238 - Poststress doppler ankle pressures: a comparison of treadmill exercise with two other m... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-2-18 |
Journal Detail:
|
Title: European journal of applied physiology Volume: - ISSN: 1439-6327 ISO Abbreviation: - Publication Date: 2011 Feb |
Date Detail:
|
Created Date: 2011-2-18 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100954790 Medline TA: Eur J Appl Physiol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Laboratori de Ciències de l'Activitat Física, Department of Fundamental Biology and Health Sciences, Research group on Communitarian Nutrition and Oxidative Stress, iUNICS, Universitat de les Illes Balears, Ctra. Valldemossa Km 7.5, 07122, Palma de Mallorca, Illes Balears, Spain. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Adenosine 5'-Triphosphate-Sensitive Potassium Channel Activator Induces the Up-Regulation of Caveoli...
Next Document: Clinical practice guidelines to inform evidence-based clinical practice.