Document Detail

Phytochemicals of cranberries and cranberry products: characterization, potential health effects, and processing stability.
MedLine Citation:
PMID:  20443158     Owner:  NLM     Status:  MEDLINE    
Emerging evidence is elucidating how non-nutrient phytochemicals underlie the health promotion afforded by fruits and vegetables. This review focuses on Vaccinium macrocarpon, the American cranberry, compiling a comprehensive list of its known phytochemical components, and detailing their prevalence in cranberry fruit and its products. Flavonoids, especially colored anthocyanins, abundant flavonols, and unique proanthocyanidins, have attracted major research attention. Other notable active components include phenolic acids, benzoates, hydroxycinnamic acids, terpenes and organic acids. Health effects of cranberries, cranberry products, and isolated cranberry components in humans and animals, as well as in vitro, are debated. Evidence for protection from several bacterial pathogens, cancer, cardiovascular disease, and inflammation is compelling, while neuroprotection and anti-viral activity also have begun to draw new consideration. Emerging bioavailability data is considered and potential molecular mechanisms are evaluated, linking phytochemicals to health effects through their biochemical properties and reactions. Finally, the effects of processing and storage on cranberry phytochemicals is discussed, with a focus on identifying research gaps and novel means to preserve their natural, health-promoting components.
E Pappas; K M Schaich
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Critical reviews in food science and nutrition     Volume:  49     ISSN:  1549-7852     ISO Abbreviation:  Crit Rev Food Sci Nutr     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2010-05-05     Completed Date:  2010-08-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8914818     Medline TA:  Crit Rev Food Sci Nutr     Country:  England    
Other Details:
Languages:  eng     Pagination:  741-81     Citation Subset:  IM    
Department of Food Science, Rutgers University, New Brunswick, NJ 08901-8520, USA.
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MeSH Terms
Anthocyanins / analysis
Biological Availability
Flavonoids / analysis*,  therapeutic use
Flavonols / analysis*,  therapeutic use
Food Preservation
Health Food
Plant Extracts / therapeutic use*
Proanthocyanidins / analysis
Vaccinium macrocarpon / chemistry*
Reg. No./Substance:
0/Anthocyanins; 0/Flavonoids; 0/Flavonols; 0/Plant Extracts; 0/Proanthocyanidins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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