| Physostigmine in the treatment of gamma-hydroxybutyric acid overdose. | |
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MedLine Citation:
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PMID: 10761496 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The widespread abuse of the recreational drug gamma-hydroxybutyric acid has resulted in several reports of overdose leading to coma. The use of a short-acting anticholinesterase agent such as physostigmine as a potential reversal agent has been proposed previously. We report 2 cases of gamma-hydroxybutyric acid-induced coma that rapidly reversed with intravenous administration of physostigmine. |
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Authors:
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S W Yates; A J Viera |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Mayo Clinic proceedings. Mayo Clinic Volume: 75 ISSN: 0025-6196 ISO Abbreviation: Mayo Clin. Proc. Publication Date: 2000 Apr |
Date Detail:
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Created Date: 2000-05-04 Completed Date: 2000-05-04 Revised Date: 2007-10-29 |
Medline Journal Info:
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Nlm Unique ID: 0405543 Medline TA: Mayo Clin Proc Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 401-2 Citation Subset: AIM; IM |
Affiliation:
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North Texas Medical Group, Colony 75056-2062, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cholinesterase Inhibitors / therapeutic use* Female Humans Hydroxybutyrates / adverse effects* Male Overdose / drug therapy Physostigmine / therapeutic use* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Cholinesterase Inhibitors; 0/Hydroxybutyrates; 57-47-6/Physostigmine; 591-81-1/4-hydroxybutyric acid |
| Comments/Corrections | |
Comment In:
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Mayo Clin Proc. 2000 Aug;75(8):871-2; author reply 872-3
[PMID:
10943249
]
Mayo Clin Proc. 2000 Aug;75(8):872-3 [PMID: 10943250 ] |
Erratum In:
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Mayo Clin Proc 2000 Aug;75(8):873 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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