Document Detail


Physiopathological mechanism of sarcopenia.
MedLine Citation:
PMID:  21824553     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The etiology of sarcopenia is multifactorial but still poorly understood, and the sequelae of this phenomenon represent a major public health issue. Age-related loss of muscle mass can be counteracted by adequate metabolic interventions including nutritional intake and exercise training. Other strategies including changes in daily protein pattern, the speed of protein digestion, or specific amino acid supplementation may be beneficial to improve short-term muscle anabolic response in elderly people. A multimodal approach combining nutrition, exercise, hormones, and specific anabolic drugs may be an innovative treatment for limiting the development of sarcopenia with aging.
Authors:
Stéphane Walrand; Christelle Guillet; Jérome Salles; Noël Cano; Yves Boirie
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinics in geriatric medicine     Volume:  27     ISSN:  1557-8623     ISO Abbreviation:  Clin. Geriatr. Med.     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-08-09     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8603766     Medline TA:  Clin Geriatr Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  365-85     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Affiliation:
INRA, UMR 1019, UNH, CRNH Auvergne, Clermont-Ferrand, F-63009, France; Université Clermont 1, UFR de Médecine, UMR 1019, UNH, Clermont-Ferrand, F-63001, France.
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