Document Detail


Physiology of transition from intrauterine to extrauterine life.
MedLine Citation:
PMID:  23164177     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The transition from fetus to newborn is the most complex adaptation that occurs in human experience. Lung adaptation requires coordinated clearance of fetal lung fluid, surfactant secretion, and onset of consistent breathing. The cardiovascular response requires striking changes in blood flow, pressures, and pulmonary vasodilation. Energy metabolism and thermoregulation must be quickly controlled. The primary mediators that prepare the fetus for birth and support the multiorgan transition are cortisol and catecholamine. Abnormalities in adaptation are frequently found following preterm birth or cesarean delivery at term, and many of these infants need delivery room resuscitation to assist in this transition.
Authors:
Noah H Hillman; Suhas G Kallapur; Alan H Jobe
Related Documents :
24829827 - Hyperammonemia: a report of maternal biliary cirrhosis and neonatal outcome.
9394897 - Respiratory function parameters in infants using inductive plethysmography.
22641277 - Resistin and leptin in breast milk and infants in early life.
16998587 - Calcineurin/nfat signaling is required for perinatal lung maturation and function.
10438197 - Functional residual capacity and pulmonary mechanics in premature infants receiving a 1...
15244227 - Randomized controlled trial of skin-to-skin contact from birth versus conventional incu...
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Clinics in perinatology     Volume:  39     ISSN:  1557-9840     ISO Abbreviation:  Clin Perinatol     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-20     Completed Date:  2013-05-24     Revised Date:  2013-12-04    
Medline Journal Info:
Nlm Unique ID:  7501306     Medline TA:  Clin Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  769-83     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adaptation, Physiological*
Body Temperature Regulation / physiology
Cardiovascular Physiological Phenomena*
Catecholamines / physiology
Delivery, Obstetric
Energy Metabolism / physiology
Female
Fetus / physiology*
Humans
Hydrocortisone / physiology
Infant, Newborn
Lung / physiology*
Pregnancy
Thyroid Hormones / physiology
Grant Support
ID/Acronym/Agency:
K08 HL097085/HL/NHLBI NIH HHS; K08-HL097085/HL/NHLBI NIH HHS; R01 HD072842/HD/NICHD NIH HHS; R01-HD072842/HD/NICHD NIH HHS
Chemical
Reg. No./Substance:
0/Catecholamines; 0/Thyroid Hormones; WI4X0X7BPJ/Hydrocortisone
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Identification, assessment and management of fetal compromise.
Next Document:  Cellular biology of end organ injury and strategies for prevention of injury.