| Physiology of transition from intrauterine to extrauterine life. | |
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MedLine Citation:
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PMID: 23164177 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The transition from fetus to newborn is the most complex adaptation that occurs in human experience. Lung adaptation requires coordinated clearance of fetal lung fluid, surfactant secretion, and onset of consistent breathing. The cardiovascular response requires striking changes in blood flow, pressures, and pulmonary vasodilation. Energy metabolism and thermoregulation must be quickly controlled. The primary mediators that prepare the fetus for birth and support the multiorgan transition are cortisol and catecholamine. Abnormalities in adaptation are frequently found following preterm birth or cesarean delivery at term, and many of these infants need delivery room resuscitation to assist in this transition. |
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Authors:
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Noah H Hillman; Suhas G Kallapur; Alan H Jobe |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinics in perinatology Volume: 39 ISSN: 1557-9840 ISO Abbreviation: Clin Perinatol Publication Date: 2012 Dec |
Date Detail:
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Created Date: 2012-11-20 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7501306 Medline TA: Clin Perinatol Country: United States |
Other Details:
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Languages: eng Pagination: 769-83 Citation Subset: IM |
Copyright Information:
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Copyright © 2012 Elsevier Inc. All rights reserved. |
Affiliation:
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Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, 3333 Burnet Avenue, ML#7029, Cincinnati, OH 45229-3039, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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