| Physiology of penile erection and pathophysiology of erectile dysfunction. | |
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MedLine Citation:
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PMID: 16291031 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This article reviews the physiology of penile erection, the components of erectile function, and the pathophysiology of erectile dysfunction. The molecular and clinical under-standing of erectile function continues to gain ground at a particularly fast rate. Advances in gene discovery have aided greatly in working knowledge of smooth muscle relaxation/contraction pathways. The understanding of the nitric oxide pathway has aided not only in the molecular understanding of the tumescence but also greatly in the therapy of erectile dysfunction. |
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Authors:
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Robert C Dean; Tom F Lue |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: The Urologic clinics of North America Volume: 32 ISSN: 0094-0143 ISO Abbreviation: Urol. Clin. North Am. Publication Date: 2005 Nov |
Date Detail:
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Created Date: 2005-11-18 Completed Date: 2006-01-19 Revised Date: 2010-12-03 |
Medline Journal Info:
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Nlm Unique ID: 0423221 Medline TA: Urol Clin North Am Country: United States |
Other Details:
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Languages: eng Pagination: 379-95, v Citation Subset: AIM; IM |
Affiliation:
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Department of Urology, University of California-San Francisco, San Francisco Medical Center, San Francisco, CA 94143-0738, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Erectile Dysfunction
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physiopathology* Hemodynamics Humans Male Muscle Contraction Muscle, Smooth / physiology Penile Erection / physiology* Penis / anatomy & histology, physiology |
| Grant Support | |
ID/Acronym/Agency:
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R01 DK045370-04/DK/NIDDK NIH HHS; R01 DK045370-05/DK/NIDDK NIH HHS; R01 DK045370-06/DK/NIDDK NIH HHS; R37 DK045370-07A1/DK/NIDDK NIH HHS; R37 DK045370-08/DK/NIDDK NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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