Document Detail

Physiology of isolated anomalous pulmonary venous connection of a single pulmonary vein as determined by cardiac magnetic resonance imaging.
MedLine Citation:
PMID:  16784931     Owner:  NLM     Status:  MEDLINE    
The physiology of isolated partially anomalous pulmonary venous connection of a single pulmonary vein has yet to be fully characterized. This study assessed the magnitude of the left-to-right shunt and right ventricular (RV) dilation from a single anomalous pulmonary vein using cardiac magnetic resonance imaging. Subjects with >1 anomalous pulmonary vein or associated lesions, including atrial septal defects, were excluded. In the 6 subjects identified, the median pulmonary-to-systemic flow ratio was 1.55 (range 1.3 to 1.6). The mean RV end-diastolic volume indexed to body surface area in the subjects was significantly larger than in a normal reference cohort (108 +/- 16 vs 78 +/- 18 cm(3)/m(2), p = 0.0009) and greater than the upper limit of normal in all 6 subjects. Older age did not correlate with increased magnitude of shunting (r = 0.3, p = 0.5), but increased age did correlate with RV end-diastolic volume indexed to body surface area (r = 0.96, p = 0.01). Isolated partially anomalous pulmonary venous connection with only 1 vein connecting anomalously results in a modest left-to-right shunt and mild RV dilation.
Joshua L Dyme; Ashwin Prakash; Beth F Printz; Avnit Kaur; Ira A Parness; James C Nielsen
Publication Detail:
Type:  Journal Article     Date:  2006-05-09
Journal Detail:
Title:  The American journal of cardiology     Volume:  98     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-06-20     Completed Date:  2006-08-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  107-10     Citation Subset:  AIM; IM    
Division of Pediatric Cardiology, Columbia University College of Physicians and Surgeons, New York, New York, USA.
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MeSH Terms
Heart Defects, Congenital / diagnosis,  physiopathology*
Magnetic Resonance Angiography / methods*
Pulmonary Veins / abnormalities*,  physiopathology
Stroke Volume

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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