| Physiology of breathing and related pathological processes in infants. | |
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MedLine Citation:
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PMID: 14992459 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There is little information describing control of breathing in the fetus and infant. The available data have largely been drawn from studies in animals and awake adults. Although the hierarchy of control of breathing is the same in adults and infants, feedback emphasis is different, with behavioral states and the sleep/wake cycle primary in the fetus and infant and integrated chemoreceptor response primary in the older child and adult. Control of breathing during the transition from the fetal state to a breathing child and the process of maturation are very different from that in adults. The article begins with an overview of the changes in the systems responsible for breathing at the developmental stages from fetus to neonate, with differences highlighted. It then discusses the possible pathology related to difficulties in negotiating this transition period, including apnea, sudden infant death syndrome, and chemoreceptor control abnormalities. |
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Authors:
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Deborah C Givan |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Seminars in pediatric neurology Volume: 10 ISSN: 1071-9091 ISO Abbreviation: Semin Pediatr Neurol Publication Date: 2003 Dec |
Date Detail:
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Created Date: 2004-03-02 Completed Date: 2004-04-05 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 9441351 Medline TA: Semin Pediatr Neurol Country: United States |
Other Details:
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Languages: eng Pagination: 271-80 Citation Subset: IM |
Affiliation:
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Indiana University School of Medicine, Indianapolis, IN, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Apnea / physiopathology Cardiovascular Physiological Phenomena* Fetus / physiopathology* Humans Hypoventilation / physiopathology Infant Infant, Newborn Models, Cardiovascular Respiration* Sudden Infant Death / pathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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