Document Detail


Physiology, Not Chronology, Dictates Outcomes after Esophagectomy for Esophageal Cancer: Outcomes in Patients 80 Years and Older.
MedLine Citation:
PMID:  23117475     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
PURPOSE: To assess short and long-term outcomes for patients aged ≥80 years undergoing esophagectomy for malignancy. METHODS: All patients undergoing esophagectomy for cancer between 1991 and 2011 had information prospectively entered into a database; patients were divided into elderly (≥80 years) and younger (<80 years) groups. RESULTS: Of the 500 patients included, 32 (6.4 %) were ≥80 years of age. Octogenarians had increased Charlson comorbidity index and were less likely to receive neoadjuvant chemoradiotherapy (6.3 vs. 39.7 %). Analysis of operative time, estimated blood loss, and length of intensive care unit and hospital stay revealed no significant differences between the groups. Patients ≥80 years old had increased total postoperative morbidity (68.8 vs. 44.9 %), specifically arrhythmia (31.3 vs. 16.7 %) and pneumonia (18.8 vs. 8.3 %). There were no in-hospital mortalities in patients ≥80 years (0 vs. 0.4 %), and there was no significant difference in overall survival between the groups (53.2 ± 9.1 vs. 77.6 ± 4.8 months; P = 0.58). Subset analysis demonstrated similar morbidity and length of hospital stay for patients between 70 and 79 years (n = 132) and those ≥80 years. CONCLUSIONS: Elderly patients undergoing esophagectomy are at greater risk of postoperative complications. However, there were no significant differences in other major parameters, including length of hospital stay, mortality, and survival, indicating that selected patients ≥80 years old can and should be assessed by an experienced surgeon.
Authors:
Sheraz R Markar; Donald E Low
Related Documents :
9155995 - Delayed surgery for ruptured intracranial aneurysms: a reappraisal.
2895995 - Effect of beta-adrenergic blockade on the growth rate of abdominal aortic aneurysms.
20557185 - Long-term follow-up of secondary interventions after endovascular aneurysm repair with ...
11404125 - Endovascular treatment of acute bleeding complications in traumatic aortic rupture and ...
19997785 - Pilot data on the endoscopic placement of covered metal stents to treat gastrojejunal l...
25347635 - A systematic review comparing furlow double-opposing z-plasty and straight-line intrave...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-2
Journal Detail:
Title:  Annals of surgical oncology     Volume:  -     ISSN:  1534-4681     ISO Abbreviation:  Ann. Surg. Oncol.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9420840     Medline TA:  Ann Surg Oncol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Thoracic Surgery, Virginia Mason Medical Center, Seattle, WA, USA, sheraz_markar@hotmail.com.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The Impact of Preoperative Lymph Node Size on Long-Term Outcome Following Curative Gastrectomy for G...
Next Document:  Frequent Alterations of MCPH1 and ATM are Associated with Primary Breast Carcinoma: Clinical and Pro...