| Physiological studies of exocrine pancreatic secretion in conscious rats. 1. Communication: surgical methods and registration techniques. | |
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MedLine Citation:
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PMID: 7434855 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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1. Two surgical methods are described to derive bile and pancreatic juice separately by indwelling catheters in rats. 2. The secretes are always recirculated into the animals duodenum, the indwelling catheters forming an extracorporal loop. 3. The experiments are performed in the conscious animal. 4. The flow rate of the secretes is measured by drop-counting with resetting after a definite number of drops (staircase registration). 5. By interposed flow-through transducers several parameters can be determined f. i. by ion-selective-electrodes and microphotometers. 6. Additional analytic measurements can be carried out in samples. 7. There is a time-shift between the recorded curves corresponding to several different flow-through transducers placed one after the other in the extracorporal circuit of flow. This time shift is variable due to the dead spaces of the system and the actual flow-rate. The theoretical aspects of this general problem are discussed in detail. 8. Sampling of pancreatic juice causes immediately a pronounced increase of flow rate and the amount of protein secreted. Therefore, volumes taken must be given back quantitatively into the animals duodenum in order to avoid a disturbance of the normal secretion pattern. |
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Authors:
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F J Haberich; T Bozkurt; W Reschke |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Zeitschrift für Gastroenterologie Volume: 18 ISSN: 0044-2771 ISO Abbreviation: Z Gastroenterol Publication Date: 1980 Aug |
Date Detail:
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Created Date: 1981-01-26 Completed Date: 1981-01-26 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0033370 Medline TA: Z Gastroenterol Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 427-35 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Catheters, Indwelling Female Methods Pancreatic Juice / physiology* Rats Transducers |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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