| Physiological response to moderate exercise workloads in a pulmonary rehabilitation program in patients with varying degrees of airflow obstruction. | |
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MedLine Citation:
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PMID: 10559076 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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STUDY OBJECTIVES: To investigate whether a 12-week pulmonary rehabilitation program that includes moderately intensive exercise training performed twice weekly can induce a training effect in patients with a wide variation of airflow limitation. PARTICIPANTS: Sixty patients with COPD (38 men) with a mean +/- SD FEV(1) % predicted of 55.1 +/- 19.8 (range, 0.51 to 2.99). All patients performed identical incremental symptom-limited cycle ergometer testing before and after a 12-week study period. Measurements and results: After 12 weeks, the patients demonstrated a significant (p < 0.05) increase in the peak values for work rate (WR; 77 +/- 30 vs 91 +/- 36 W) and oxygen uptake (1.14 +/- 0.45 vs 1.20 +/- 0.52 L/min). Furthermore, at a given WR during incremental symptom-limited cycle ergometer testing, there were significant (p < 0.05) reductions in minute ventilation (42.4 +/- 16.1 vs 37.0 +/- 13. 6 L/min), carbon dioxide output (1.13 +/- 0.49 vs 1.03 +/- 0.42 L/min), ventilatory equivalent for oxygen (37.6 +/- 8.1 vs 36.0 +/- 6.3), and heart rate (135 +/- 15 vs 128 +/- 16 beats/min). None of the observed physiologic changes correlated with FEV(1) % predicted. CONCLUSIONS: A pulmonary rehabilitation program performed twice weekly with moderate exercise workloads can lead to a physiologic training response irrespective of the degree of airflow limitation. |
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Authors:
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I Vogiatzis; A F Williamson; J Miles; I K Taylor |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Chest Volume: 116 ISSN: 0012-3692 ISO Abbreviation: Chest Publication Date: 1999 Nov |
Date Detail:
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Created Date: 1999-11-30 Completed Date: 1999-11-30 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0231335 Medline TA: Chest Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1200-7 Citation Subset: AIM; IM |
Affiliation:
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School of Health Sciences, University of Sunderland, Sunderland Royal Hospital, Sunderland, UK. vogiatzis@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Exercise
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physiology* Exercise Test Exercise Therapy* Female Forced Expiratory Volume Humans Lung Diseases, Obstructive / metabolism, physiopathology, rehabilitation* Male Middle Aged Outpatients Oxygen Consumption Vital Capacity |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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